![]() MR Imaging of Adverse Local Tissue Reactions around Rejuvenate Modular Dual-Taper Stems. Burge AJ, Gold SL, Lurie B, Nawabi DH, Fields KG, Koff MF, Westrich G, Potter HG. Adverse reactions to metal debris: histopathological features of periprosthetic soft tissue reactions seen in association with failed metal on metal hip arthroplasties. Natu S, Sidaginamale RP, Gandhi J, Langton DJ, Nargol AV. (2014) Radiographics : a review publication of the Radiological Society of North America, Inc. Glossary of terms for musculoskeletal radiology. Griffith, Philip Robinson, Christian W.A. William Palmer, Laura Bancroft, Fiona Bonar, Jung-Ah Choi, Anne Cotten, James F. (2010) Journal of radiology case reports. Metallosis and Metal-Induced Synovitis Following Total Knee Arthroplasty: Review of Radiographic and CT Findings. Vivegananthan B, Shah R, Karuppiah AS, Karuppiah SV. complications of knee joint replacements.complications of hip joint replacements.Resultant tissue necrosis and mass-like pseudotumors are indicative of adverse local tissue reaction to the metallic microparticles 3. Microdebris collections are typically low on T2W sequences unlike, for example, seromas. ![]() Magnetic susceptibility ( blooming) artifacts might be present. metal line sign: thin rim of increased linear density outlining a portion of the joint capsule.ĬT is better at demonstrating the dense collections of microdebris 3.cloud sign: presence of an amorphous cloudy density within the soft tissues adjacent to the prosthesis.bubble sign: curvilinear radiodensity surrounding the replacement.Several plain film signs have been described: Radiographic features Plain radiographĪs metallosis is a result of hardware failure, signs of it are most commonly present. Metallosis tends to involve large, weight-bearing joints, such as knees and hips. Metallosis should not be confused with particle disease, which is caused by the release of nonmetallic polyethylene microparticles from the prosthesis liner 3. The debris can involve the joint capsule, cavity, and/or extra-articular tissues. Plural for an atom or molecule with a net electric charge. Plural for a small round particle of substance. Metallic microparticles are generated from repetitive abrasion of metallic hardware, such as from metal-on-metal arthroplasty, modular reconstruction components (such as at the prosthetic femoral head–neck interface, called trunnionosis), or fractured fixation plates 1. Very fine solid or liquid particles suspended in the air, slightly limiting visibility. Metallosis is the deposition of metallic debris into periprosthetic soft tissues. When used to describe the biologic reaction (as opposed to the inciting metal deposition), "pure metallosis" has been defined histologically as the predominance of macrophages containing metallic particles (i.e., histocytic foreign body reaction), without the presence of a chronic lymphocytic infiltrate to suggest an aseptic lymphocyte-dominant vasculitis-associated lesion (ALVAL) and type IV delayed type hypersensitivity reaction 5,6. However, the nature of the biologic response that accompanies metal deposition is variable. I’ll also change the color a little bit since the page background is white.Metallosis is sometimes used as a synonym for the umbrella term adverse reaction to metal debris 4.
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